Biotemplated nanopatterning of planar surfaces with molecular motors.
basic_science · Level V
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Abstract
We report on the generation of nanometer-wide, non-topographical patterns of proteins on planar surfaces. In particular, we used the regular lattice of reconstituted microtubules as template structures to specifically bind and transfer kinesin-1 and nonclaret disjunctional motor proteins. The generated tracks, which comprise dense and structurally oriented arrays of functional motor proteins, proved to be highly efficient for the guiding of microtubule transporters.
Medical subject headings
- Crystallization
- Kinesins
- Microtubules
- Molecular Motor Proteins
- Nanostructures