Reactivation of 2 genetically distinct varicella-zoster viruses in the same individual.

Taha, Y; Scott, F T; Parker, S P; Syndercombe Court, D; Quinlivan, M L; Breuer, J · Clin Infect Dis · 2006

case_report · Level V

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Abstract

Varicella-zoster viruses recovered from 2 episodes of herpes zoster in an immunocompetent man were found to be different genotypes. The fact that the 2 isolates came from the same individual was confirmed by DNA fingerprinting. Immunity following chickenpox may not always protect against systemic reinfection. This finding raises questions about varicella-zoster virus pathogenesis and may have an impact on public health policy.

Medical subject headings