Nodular basal cell carcinoma in Gorlin's syndrome treated with systemic photodynamic therapy and interstitial optical fiber diffuser laser.

Madan, Vishal; Loncaster, Juliette A; Allan, Donald; Lear, John T; Sheridan, Linda; Leach, Catherine; Allan, Ernest · J Am Acad Dermatol · 2006

case_report · Level V

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Abstract

Nodular basal cell carcinomas resistant to multiple forms of treatment in two patients with nevoid basal cell carcinoma syndrome (Gorlin's syndrome) were treated with systemic porfimer sodium-based photodynamic therapy. Interstitially placed optical diffuser fibers were used to deliver light. Good response to treatment was seen on clinical evaluation and on measurement by a 20-MHz high-resolution ultrasound.

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