Comparative pilot study of symptoms and quality of life in cancer patients and patients with end stage renal disease.

Abstract

Patients with advanced renal failure are increasingly opting for conservative treatment, yet little is known of their palliative care needs. We performed a cross-sectional study, examining symptom burden and quality of life in patients with advanced renal failure (estimated GFR < 17 mL/min; n = 11). A contemporary cohort with terminal malignancy acted as comparators (n = 11). Symptom burden was scored using an extended Memorial Symptom Assessment Scale Short Form questionnaire. Quality of life was assessed using the Euroqol-5Q questionnaire. Demographic and pathological data, performance status and co-morbidity were also recorded. Baseline characteristics were similar for the two groups. Symptom burden (renal 17; cancer 15; P =NS) and quality of life scores (renal 60; cancer 60; P =NS) were remarkably similar. Both groups reported high levels of psychological distress. Patients with advanced renal failure experience a symptom burden and impairment of quality of life similar to that of patients with terminal malignancy.