Diagnostic challenges in facioscapulohumeral muscular dystrophy.

Sacconi, S; Salviati, L; Bourget, I; Figarella, D; Péréon, Y; Lemmers, R; van der Maarel, S; Desnuelle, C · Neurology · 2006

case_series · Level IV

Where this comes from

Abstract

The diagnosis of facioscapulohumeral muscular dystrophy (FSHD) can be difficult due to its clinical variability and complex genetic cause. We present three challenging cases: one misdiagnosis of FSHD, one patient with FSHD resembling mitochondrial myopathy, and one patient with combined FSHD and limb girdle muscular dystrophy 2A. Detailed clinical and genetic evaluation, including 4qA/4qB allele determination, may be needed for the diagnosis of FSHD.

Medical subject headings

Anatomy