GECO--linear visualization for comparative genomics.

Kuenne, C T; Ghai, R; Chakraborty, T; Hain, T · Bioinformatics · 2007

basic_science · Level V

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Abstract

In order to understand and interpret phylogenetic and functional relationships between multiple prokaryotic species, qualitative and quantitative data must be correlated and displayed. GECO allows linear visualization of multiple genomes using a client/server based approach by dynamically creating .png- or .pdf-formatted images. It is able to display ortholog relations calculated using BLASTCLUST by color coding ortholog representations. Irregularities on the genomic level can be identified by anomalous G/C composition. Thus, this software will enable researchers to detect horizontally transferred genes, pseudogenes and insertions/deletions in related microbial genomes. http://bioinfo.mikrobio.med.uni-giessen.de/geco2/GecoMainServlet

Medical subject headings