Dynamic helix interactions in transmembrane signaling.
review · Level V
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- Record sourced from PubMed, PMID 17081964.
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Abstract
Studying how protein transmembrane domains transmit signals across membranes is beset by unique challenges. Here, we discuss the circumstances that have led to success and reflect on what has been learned from these examples. Such efforts suggest that some of the most interesting properties of transmembrane helix interactions may be the least amenable to study by current techniques.
Medical subject headings
- Membrane Proteins
- Signal Transduction