Current rectification with poly-l-lysine-coated quartz nanopipettes.

Umehara, Senkei; Pourmand, Nader; Webb, Chris D; Davis, Ronald W; Yasuda, Kenji; Karhanek, Miloslav · Nano Lett · 2006

basic_science · Level V

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Abstract

Ion current rectification with quartz nanopipette electrodes was investigated through the control of the surface charge. The presence and absence of a positively charged poly-l-lysine (PLL) coating resulted in the rectified current with opposite polarity. The results agreed with the theories developed for current-rectifying conical nanopores, suggesting the similar underlying mechanism among asymmetric nanostructure in general. This surface condition dependence can be used as the fundamental principle of multi-purpose real-time in vivo biosensors.

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