Medium scale integration of molecular logic gates in an automaton.
basic_science · Level V
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Abstract
The assembly of molecular automata that perform increasingly complex tasks, such as game playing, presents an unbiased test of molecular computation. We now report a second-generation deoxyribozyme-based automaton, MAYA-II, which plays a complete game of tic-tac-toe according to a perfect strategy. In silicon terminology, MAYA-II represents the first "medium-scale integrated molecular circuit", integrating 128 deoxyribozyme-based logic gates, 32 input DNA molecules, and 8 two-channel fluorescent outputs across 8 wells.
Medical subject headings
- Artificial Intelligence
- Computers, Molecular
- Computing Methodologies
- DNA, Catalytic
- Information Storage and Retrieval