Acitretin induces capillary leak syndrome in a patient with pustular psoriasis.

Vos, Lydia E; Vermeer, Maarten H; Pavel, Stan · J Am Acad Dermatol · 2007

case_report · Level V

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Abstract

Capillary leak syndrome is a rare and potentially life-threatening condition caused by a shift of intravascular fluid and proteins to the interstitial space. We describe a patient with pustular psoriasis in whom capillary leak syndrome developed after the start of acitretin. Immediate withdrawal of retinoic acid is necessary and corticosteroid therapy should be considered.

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