Bullous pemphigoid associated with hypereosinophilic syndrome: simultaneous response to imatinib.

Hofmann, Silke C; Technau, Kristin; Müller, Antonia M S; Lübbert, Michael; Bruckner-Tuderman, Leena · J Am Acad Dermatol · 2007

case_report · Level V

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Abstract

Hypereosinophilic syndrome is a myeloproliferative disorder defined by unexplained, persistent hypereosinophilia with cutaneous or systemic involvement. We describe a patient with coexistence of hypereosinophilic syndrome and bullous pemphigoid. Treatment with the novel tyrosine kinase inhibitor imatinib mesylate resulted in durable remission of hypereosinophilia and skin lesions.

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