Assessment of the utility of viral culture of cerebrospinal fluid.
cross_sectional · Level IV
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- Record sourced from PubMed, PMID 17109291.
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Abstract
Nucleic acid amplification testing is the preferred method to detect enteroviruses and Herpesviridae in cerebrospinal fluid, but clinicians still request viral culture. Review of 22,394 viral cultures of cerebrospinal fluid samples found that <0.1% recovered nonenterovirus, non-Herpesviridae species, suggesting that, when nucleic acid amplification testing is performed, viral culture may have no additional benefit.
Medical subject headings
- Enterovirus
- Herpesviridae
- Nucleic Acid Amplification Techniques