Antibiotic drug interactions.

Pai, Manjunath P; Momary, Kathryn M; Rodvold, Keith A · Med Clin North Am · 2006

review · Level V

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Abstract

Drug-drug interactions in the field of infectious diseases continue to expand as new drugs are approved, metabolic enzymes and transporters are identified, and recommendations for co-administration of drugs are revised. This article provides an overview of the principles and mechanisms of drug-drug interactions and describes pharmacokinetic-pharmacodynamic interactions commonly associated with antibacterial therapy, antiviral agents (non-retroviral), and drugs for tuberculosis.

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