SNP2NMD: a database of human single nucleotide polymorphisms causing nonsense-mediated mRNA decay.
Where this comes from
- Record sourced from PubMed, PMID 17121775.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Elucidating the effects of genetic polymorphisms on genes and gene networks is an important step in disease association studies. We developed the SNP2NMD database for human SNPs (single nucleotide polymorphisms) that result in PTCs (premature termination codons) and trigger nonsense-mediated mRNA decay (NMD). The SNP2NMD Web interfaces provide extensive genetic information on and graphical views of the queried SNP, gene, and disease terms. SNP2NMD is available from http://variome.net, or directly from http://bioportal.kobic.re.kr/SNP2NMD. http://bioportal.kobic.re.kr/SNP2NMD/Wiki.jsp?page=Statistics.
Medical subject headings
- Chromosome Mapping
- Codon, Nonsense
- DNA Mutational Analysis
- Databases, Genetic
- Genome, Human
- Polymorphism, Single Nucleotide
- RNA Stability