Re-evaluating cell-cycle regulation by E2Fs.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 17129771.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Activation of E2F transcription factors is thought to drive the expression of genes essential for the transition of cells from G1 to S phase and for the initiation of DNA replication. However, this textbook view of E2Fs is increasingly under challenge. Here we discuss an alternative model for how E2Fs may work.
Medical subject headings
- Cell Cycle
- E2F Transcription Factors