ER targeting signals: more than meets the eye?
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 17129773.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
The signal sequences that target newly synthesized proteins to the endoplasmic reticulum are highly variable; however, the functional significance of this diversity has remained obscure. In this issue, Kang et al. (2006) report that variability in signal sequences allows the cell to selectively regulate the translocation of proteins into the endoplasmic reticulum in a substrate-specific manner.
Medical subject headings
- Endoplasmic Reticulum
- Protein Sorting Signals