Acute hypothalamic stimulation and ongoing cluster headache attacks.

Leone, M; Franzini, A; Broggi, G; Mea, E; Cecchini, A Proietti; Bussone, G · Neurology · 2006

case_series · Level IV

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Abstract

Long-term hypothalamic stimulation is effective in improving drug-resistant chronic cluster headache (CH). We assessed acute hypothalamic stimulation to resolve ongoing CH attacks in 16 patients implanted to prevent chronic CH, investigating 136 attacks. A pain intensity reduction of > or =50% occurred in 25 of 108 evaluable attacks (23.1%). Acute hypothalamic stimulation is not effective in resolving ongoing CH attacks, suggesting that hypothalamic stimulation acts by complex mechanisms in CH prevention.

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