Efficacy of carbamazepine and valproate as monotherapy for early epilepsy and single seizures.
rct · Level II
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Abstract
In the Multi-Centre Study of Early Epilepsy and Single Seizures (MESS), patients were randomly allocated to immediate or delayed antiepileptic drug treatment. For time to first seizure recurrence, MESS provides strong evidence of an effect for carbamazepine as monotherapy but mixed evidence of an effect for valproate.
Medical subject headings
- Anticonvulsants
- Carbamazepine
- Epilepsy
- Valproic Acid