Protein nutrition as therapy for a genetic disorder of bone?
other · Level V
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Abstract
Bone formation is controlled by a network of transcription factors and signaling molecules. In this issue, , studying the role of the transcription factor ATF4 in a new mouse model of neurofibromatosis type I skeletal defects, demonstrate striking effects of changing dietary protein on bone formation abnormalities.
Medical subject headings
- Activating Transcription Factor 4
- Bone Diseases, Developmental
- Dietary Proteins
- Neurofibromin 1
- Osteoblasts