Molecular regulation of HDL metabolism and function: implications for novel therapies.
review · Level V
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- Record sourced from PubMed, PMID 17143322.
- Also identified by PMC identifier 1679714.
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Abstract
HDL metabolism represents a major target for the development of therapies intended to reduce the risk of atherosclerotic cardiovascular disease. HDL metabolism is complex and involves dissociation of HDL apolipoprotein and HDL cholesterol metabolism. Advances in our understanding of the molecular regulation of HDL metabolism, macrophage cholesterol efflux, and HDL function will lead to a variety of novel therapeutics.
Medical subject headings
- Arteriosclerosis
- Lipoproteins, HDL