A rapid screening battery to identify frontal dysfunction in patients with ALS.

Flaherty-Craig, Claire; Eslinger, Paul; Stephens, Beth; Simmons, Zachary · Neurology · 2006

cross_sectional · Level IV

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Abstract

We studied the relationship between verbal associative fluency, verbal abstract reasoning, and judgment in ALS using a 20-minute screening evaluation. Deficiencies in these measures were found in 20.0%, 18.6%, and 35.7% of patients with limb-onset ALS and in 37.5%, 25.0%, and 60.0% of patients with bulbar-onset ALS. This simple screen identifies deficits that affect discussions of treatment interventions and end-of-life issues.

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