Comprehensive association analysis of the NOS2A gene with Parkinson disease.
case_control · Level III
Where this comes from
- Record sourced from PubMed, PMID 17159127.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Inducible nitric oxide synthase (NOS2A) may be involved in the oxidative stress pathology of Parkinson disease (PD). Two previous studies reported an association of a single nucleotide polymorphism (rs1060826) with PD. A replication study of 340 German patients and 680 controls showed no significant association between 12 genotyped polymorphisms and PD. NOS2A is therefore not a major susceptibility locus in our relatively young sample population.
Medical subject headings
- Nitric Oxide Synthase Type II
- Parkinson Disease