Potential influence of hormones in the development of slipped capital femoral epiphysis: a preliminary study.
prospective_cohort · Level II
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Abstract
The potential influence of hormonal imbalance on the development of slipped capital femoral epiphysis was assessed through a prospective clinical study. The serum levels of T3, T4, thyroid-stimulating hormone, testosterone, estradiol, dehydroepiandrosterone-sulfate, follicle-stimulating hormone, luteinizing hormone, human growth hormone, adrenal cortex hormone and cortisol were evaluated in seven boys and seven girls. Forty-three out of 154 hormonal determinations (27.9%) were abnormal. The results showed increased incidence of pathological values mainly in the levels of follicle-stimulating-hormone, luteinizing-hormone and testosterone. No patient had clinical findings of endocrinopathy. A (possibly) temporary hormonal disorder may play a potentially significant role in the development of slipped capital femoral epiphysis.
Medical subject headings
- Adrenal Cortex Hormones
- Epiphyses, Slipped
- Femur Head
- Gonadal Steroid Hormones
- Growth Hormone
- Hydrocortisone
- Thyroid Hormones
Anatomy
- femur