Microtubule capture: a concerted effort.
review · Level V
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Abstract
Kinetochores direct attachment of chromosomes to microtubules of the mitotic spindle during cell division. Three recent studies in Cell, including one in this issue, reveal important new roles for two kinetochore protein complexes-Ndc80 and INCENP-Survivin-in establishing the correct attachment of chromosomes to spindle microtubules (Cheeseman et al., 2006, DeLuca et al., 2006 and Sandall et al., 2006).
Medical subject headings
- Chromosomes
- Kinetochores
- Microtubule-Associated Proteins
- Microtubules
- Spindle Apparatus