Solvent resistant microfluidic DNA synthesizer.

Huang, Yanyi; Castrataro, Piero; Lee, Cheng-Chung; Quake, Stephen R · Lab Chip · 2007

basic_science · Level V

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Abstract

We fabricated a microfluidic DNA synthesizer out of perfluoropolyether (PFPE), an elastomer with excellent chemical compatibility which makes it possible to perform organic chemical reactions, and synthesized 20-mer oligonucleotides on chip.

Medical subject headings