The "domino theory" of hunger: the hypothalamus is hot.
editorial · Level V
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- Record sourced from PubMed, PMID 17189199.
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Abstract
Mechanisms by which the hypothalamus senses nutritional status are important for many metabolic diseases, including obesity and diabetes. Now, report that hypothalamic neurons sense nutritional deficit through a cascade of events involving leptin, corticosterone, and glial production of thyroid hormone, leading to neuronal induction of uncoupling protein.
Medical subject headings
- Hunger
- Hypothalamus
- Neurons
- Thermogenesis