Prostatic acid phosphatase, beta-glucuronidase and prostate specific antigen assays in fine needle aspirates from benign and malignant prostates.
case_control · Level III
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Abstract
Enzymatic assays for tartrate-sensitive acid phosphatase and beta-glucuronidase, and radio-immunoassay for prostate-specific antigen, were modified for application to fine-needle aspirate samples from benign and malignant human prostates. When compared to samples from benign prostates, the ratio of acid phosphatase to beta-glucuronidase activities was significantly decreased in needle aspirates from malignant prostates. Prostate-specific antigen values in the aspirates did not correlate with malignancy.
Medical subject headings
- Acid Phosphatase
- Antigens, Neoplasm
- Biomarkers, Tumor
- Clinical Enzyme Tests
- Glucuronidase
- Prostate
- Prostatic Neoplasms