Gene-environment interplay in attention-deficit hyperactivity disorder and the importance of a developmental perspective.

Thapar, Anita; Langley, Kate; Asherson, Philip; Gill, Michael · Br J Psychiatry · 2007

editorial · Level V

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Abstract

Attention-deficit hyperactivity disorder (ADHD) varies in its clinical presentation and course. Susceptibility gene variants for ADHD and associated antisocial behaviour are being identified with emerging evidence of gene-environment interaction. Genes and environmental factors that influence the origins of disorder are not necessarily the same as those that contribute to its course and outcome.

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