DNA nucleoside interaction and identification with carbon nanotubes.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 17212438.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
We investigate the interaction of individual DNA nucleosides with a carbon nanotube (CNT) in vacuum and in the presence of external gate voltage. We propose a scheme to discriminate between nucleosides on CNTs based on measurement of electronic features through a local probe such as scanning tunneling spectroscopy. We demonstrate through quantum mechanical calculations that these measurements can achieve 100% efficiency in identifying DNA bases. Our results support the practicality of ultrafast DNA sequencing using electrical measurements.
Medical subject headings
- DNA
- Nanotubes, Carbon
- Nucleosides
- Spectrum Analysis