Perforating folliculitis associated with tumour necrosis factor-alpha inhibitors administered for rheumatoid arthritis.
case_report · Level V
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- Record sourced from PubMed, PMID 17223880.
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Abstract
Perforating dermatoses are characterized by transepithelial elimination of dermal structures. We report a 61-year-old man with rheumatoid arthritis who developed a perforating folliculitis following the administration of two tumour necrosis factor (TNF)-alpha inhibitors, infliximab and etanercept. To our knowledge, no perforating disorders have been reported associated with these drugs. This report suggests, for the first time, a role for TNF-alpha in the pathogenesis of perforating folliculitis.
Medical subject headings
- Antibodies, Monoclonal
- Antirheumatic Agents
- Arthritis, Rheumatoid
- Folliculitis
- Immunoglobulin G
- Tumor Necrosis Factor-alpha