Microwave hyperthermia treatment increases heat shock proteins in human skeletal muscle.
case_series · Level IV
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- Record sourced from PubMed, PMID 17224440.
- Also identified by PMC identifier 2465355.
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Abstract
To test the hypothesis that microwave hyperthermia treatment (MHT) increases heat shock proteins (HSPs) in the human vastus lateralis muscle. Four untrained healthy male volunteers participated in this study. The lateral side of the thigh of one leg (heated leg) was heated with a microwave generator (2.5 GHz, 150 W) for 20 min. At 1 day after the MHT, a muscle sample was taken from the heated leg. A control sample was taken from the unheated leg on another day of the MHT. For both legs, HSP90, HSP72 and HSP27 levels were compared. The HSP90, HSP72 and HSP27 levels in heated legs were significantly higher than those in control legs (p<0.05). Application of MHT can increase the levels of several HSPs in human skeletal muscle.
Medical subject headings
- Heat-Shock Proteins
- Hyperthermia, Induced
- Microwaves
- Muscle, Skeletal
- Muscular Diseases