Pediatric primary CNS lymphoma: longterm survival after treatment with radiation monotherapy.
case_report · Level V
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Abstract
Primary central nervous system lymphoma (PCNSL) in childhood is very rare. We report a 5-year-old boy who presented with headache and nausea. Magnetic resonance imaging (MRI) showed a faintly enhanced lesion in the left cerebellar hemisphere. MRI-guided biopsy was returned with a histopathological diagnosis of lymphoma. Cranial radiotherapy alone with whole-brain irradiation (30 Gy) followed by a 20-Gy booster to the tumor bed was successful and the patient is alive, well, and in persistent complete remission 14 years post-treatment. This is the only pediatric PCNSL encountered at our institution between 1989 and 2004.
Medical subject headings
- Cerebellar Neoplasms
- Cranial Irradiation
- Lymphoma