High-density lipoprotein cholesterol: an emerging target for stroke treatment.

Sanossian, Nerses; Saver, Jeffrey L; Navab, Mohamad; Ovbiagele, Bruce · Stroke · 2007

review · Level V

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Abstract

This review characterizes the current state of knowledge of high-density lipoprotein (HDL) in relation to stroke. HDL has anti-atherosclerotic and anti-inflammatory properties and is an important component in atherosclerosis. Serum HDL-cholesterol levels are inversely related to heart disease and stroke risk. There are various established and experimental treatments which can raise serum HDL cholesterol and improve its function. HDL is an emerging target for atherosclerotic stroke treatment with the potential to dramatically impact the care of stroke patients.

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