Localisation of increased prefrontal white matter in pathological liars.

Yang, Yaling; Raine, Adrian; Narr, Katherine L; Lencz, Todd; LaCasse, Lori; Colletti, Patrick; Toga, Arthur W · Br J Psychiatry · 2007

case_control · Level III

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Abstract

We examined white matter volumes in four prefrontal subregions using structural magnetic resonance imaging in 10 pathological liars, 14 antisocial controls, and 20 normal controls. Liars showed a relatively widespread increase in white matter (23-36%) in orbitofrontal, middle and inferior, but not superior, frontal gyri compared with antisocial and normal controls. This white matter increase may predispose some individuals to pathological lying.

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