Severe photosensitivity causing multifocal squamous cell carcinomas secondary to prolonged voriconazole therapy.
case_report · Level V
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- Record sourced from PubMed, PMID 17278050.
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Abstract
A 32-year-old woman was treated with long-term voriconazole therapy for recurrent aspergillosis associated with chronic granulomatous disease. A short time after commencement of voriconazole therapy, a severe photosensitivity reaction developed. Continued voriconazole exposure led to the development of multifocal facial squamous cell carcinomas. The photosensitivity reaction resolved after the patient changed therapy to posaconazole.
Medical subject headings
- Antifungal Agents
- Carcinoma, Squamous Cell
- Photosensitivity Disorders
- Pyrimidines
- Skin Neoplasms
- Triazoles