Neuropsychological abnormalities in patients with dementia in CRF 01_AE HIV-1 infection.
cross_sectional · Level IV
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Abstract
HIV-associated dementia (HAD) is not firmly established in patients with circulating recombinant form (CRF) 01_AE HIV-1. In this study, we compared neuropsychological performance among 15 Thai individuals with HAD, 15 Thai individuals without HAD, and 30 HIV-negative control subjects. HIV-1 participants were highly active anti-retroviral therapy naive and matched by age, education, and CD4 count. Neuropsychological testing abnormalities were identified in most cognitive domains among HAD vs HIV-negative participants, confirming the presence of HAD in CRF01_AE.
Medical subject headings
- AIDS Dementia Complex
- HIV-1
- Mental Disorders
- Nervous System Diseases
- Recombination, Genetic