Transient neonatal hypothyroidism is associated with elevated serum anti-thyroglobulin antibody levels in newborns and their mothers.
cross_sectional · Level IV
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Abstract
Transient congenital hypothyroidism (TCH) was detected in 6 of 35,067 newborns (1:5845 births) screened in Iran. Antithyroglobulin antibodies positivity was present in 4 of 6 (66.7%) of those with TCH and in 6 of 106 (5.7%) of those with "transient hyperthyrotropinemia and normal" diagnoses (P = .0005), but positivity was similar in newborns with transient hyperthyrotropinemia versus normal neonates (P = .397).
Medical subject headings
- Autoantibodies
- Congenital Hypothyroidism
- Pregnancy Complications