Neuronal polarity: from extracellular signals to intracellular mechanisms.
review · Level V
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- Record sourced from PubMed, PMID 17311006.
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Abstract
After they are born and differentiate, neurons break their previous symmetry, dramatically change their shape, and establish two structurally and functionally distinct compartments - axons and dendrites - within one cell. How do neurons develop their morphologically and molecularly distinct compartments? Recent studies have implicated several signalling pathways evoked by extracellular signals as having essential roles in a number of aspects of neuronal polarization.
Medical subject headings
- Cell Polarity
- Neurons
- Signal Transduction