Aldosterone antagonists: silver bullet or just sodium excretion and potassium retention?
editorial · Level V
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- Record sourced from PubMed, PMID 17315004.
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Abstract
ACE inhibitors or AT(1) antagonists are powerful therapeutic strategies to slow the progression of renal disease. However, they provide only imperfect protection since they cannot always prevent end-stage renal failure. Innovative approaches are needed to keep patients with chronic kidney disease off dialysis. Blockade of the aldosterone pathway may prove to be such a beneficial therapeutic concept.
Medical subject headings
- Kidney Failure, Chronic
- Mineralocorticoid Receptor Antagonists
- Potassium
- Sodium