Centromere assembly and propagation.
review · Level V
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- Record sourced from PubMed, PMID 17320502.
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Abstract
Centromere assembly provides a unique example of how elaborate protein structures can be assembled onto DNA, independent of sequence, and then stably propagated through numerous cell divisions. Here, we review the possible epigenetic strategies that organisms ranging from yeast to human use to assemble and propagate active centromeres.
Medical subject headings
- Cell Division
- Centromere
- Chromosome Segregation
- DNA
- Epigenesis, Genetic