Phylogenetic exploration of bacterial genomic rearrangements.

Fremez, Romain; Faraut, Thomas; Fichant, Gwennaele; Gouzy, Jérôme; Quentin, Yves · Bioinformatics · 2007

basic_science · Level V

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Abstract

We present a graphical tool dedicated to the exploration of bacterial genome rearrangements. The principle of this exploration relies on the reconstruction of ancestral genomes at each internal node of a gene-order-based phylogenetic tree. This tool allows the selection of internal nodes to visualize the rearrangements between the inferred chromosome of this node and its direct descendant on the tree. PEGR is available at the Genopole Toulouse Bioinformatics platform.

Medical subject headings