Topical agents for the management of musculoskeletal pain.
review · Level V
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- Record sourced from PubMed, PMID 17349504.
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Abstract
The recent recognition of the magnitude of cardiovascular risk of both nonselective nonsteroidal anti-inflammatory drugs and COX-2 selective inhibitors, in addition to the persistent concerns about the use of opioids, has brought increased attention to nonsystemic, topical analgesics. These agents have a favorable safety profile and there is increasing evidence indicating their efficacy for a variety of pain disorders. The use of topical analgesics in the treatment of the most prevalent musculoskeletal pain syndromes is described, with a focus on mechanisms for drug delivery and clinical trials data.
Medical subject headings
- Analgesics
- Musculoskeletal Diseases
- Pain