N-WASP generates a buzz at membranes on the move.
basic_science · Level V
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Abstract
The fast-growing ends of actin filaments push against membranes to create cell-surface protrusions and to propel the movement of membrane vesicles. Co et al. (2007) now show that the neural Wiskott-Aldrich syndrome protein (N-WASP) mediates dynamic attachment between membranes and the growing ends of actin filaments to sustain membrane movement.
Medical subject headings
- Actins
- Cell Membrane
- Wiskott-Aldrich Syndrome Protein, Neuronal