SCOPing out proteases in long-term memory.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 17382874.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
The ERK1/2 MAP kinase (MAPK) signaling pathway is important for the formation of long-term memories. In this issue, Shimizu et al. (2007) provide new insight into the regulation of this pathway by demonstrating that activation of MAP kinase occurs through the calcium-dependent degradation of SCOP (suprachiasmatic nucleus circadian oscillatory protein) by the protease calpain.
Medical subject headings
- Brain
- Calpain
- Memory
- Nuclear Proteins
- Phosphoprotein Phosphatases