Unsupervised segmentation of continuous genomic data.

Day, Nathan; Hemmaplardh, Andrew; Thurman, Robert E; Stamatoyannopoulos, John A; Noble, William S · Bioinformatics · 2007

basic_science · Level V

Where this comes from

Abstract

The advent of high-density, high-volume genomic data has created the need for tools to summarize large datasets at multiple scales. HMMSeg is a command-line utility for the scale-specific segmentation of continuous genomic data using hidden Markov models (HMMs). Scale specificity is achieved by an optional wavelet-based smoothing operation. HMMSeg is capable of handling multiple datasets simultaneously, rendering it ideal for integrative analysis of expression, phylogenetic and functional genomic data. http://noble.gs.washington.edu/proj/hmmseg

Medical subject headings