Why is long-term therapy required to cure tuberculosis?

Connolly, Lynn E; Edelstein, Paul H; Ramakrishnan, Lalita · PLoS Med · 2007

review · Level V

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Abstract

The authors argue that understanding and countering general bacterial mechanisms of phenotypic antibiotic resistance may hold the key to reducing the duration of treatment of all recalcitrant bacterial infections, including tuberculosis.

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