Is there a genetic basis for Fuchs' heterochromic uveitis? Discordance in monozygotic twins.
case_report · Level V
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- Record sourced from PubMed, PMID 1739686.
- Also identified by PMC identifier 504143.
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Abstract
One pair, and probably two pairs, of monozygotic twins are reported with discordance for Fuchs' heterochromic uveitis (FHU). Regular Mendelian inheritance of this disease is now proved to be impossible. The heritability of FHU is low and may be zero. The possibility of any genetic predisposition to the disease and its association with 'simple' heterochromia are discussed.
Medical subject headings
- Diseases in Twins
- Iridocyclitis