Chylomicrons and lipoprotein lipase at the endothelial surface: bound and GAG-ged?
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 17403366.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
At the endothelial cell surface, binding of chylomicrons and lipoprotein lipase (LpL), the major enzyme involved in the processing of these triglyceride-rich lipoproteins, is thought to involve electrostatic interactions with glycosaminoglycans. A new study published in this issue of Cell Metabolism (Beigneux et al., 2007) provides evidence for a specific chylomicron/LpL receptor, which may serve as a platform for LpL-mediated processing of chylomicrons on the capillary endothelium.
Medical subject headings
- Chylomicrons
- Endothelium, Vascular
- Glycosaminoglycans
- Lipoprotein Lipase