Renaturation of DNA catalysed by yeast DNA repair and recombination protein RAD10.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 1741062.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
The RAD10 gene of Saccharomyces cerevisiae is required for the incision step of excision repair of ultraviolet-damaged DNA, and it functions in mitotic recombination. RAD10 has homology to the human excision repair gene ERCC-1. Here we describe the purification of the protein encoded by RAD10 and show that it is a DNA-binding protein with a strong preference for single-stranded DNA. We also show that RAD10 promotes the renaturation of complementary DNA strands.
Medical subject headings
- DNA Repair
- DNA, Fungal
- Endonucleases
- Fungal Proteins
- Nucleic Acid Renaturation
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins