Waiting to inhale: HIF-1 modulates aerobic respiration.

Boutin, Adam T; Johnson, Randall S · Cell · 2007

editorial · Level V

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Abstract

The hypoxia-inducible factor HIF-1 is known to promote anaerobic respiration during low oxygen conditions (hypoxia). In this issue, Fukuda et al. (2007) expand the range of HIF-1's functions by showing that it modulates aerobic respiration as well.

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